Discovery 01.
Stress reaches the pigment reserve.
Acute stress was shown to deplete melanocyte stem cells through sympathetic signalling. Greying entered the literature as a stem-cell and nerve-signalling problem.
Zhang et al, 2020 · Harvard.
Hair Labs. Kensington, London. Est. 2025.
The origin of the practice.
Hair Labs studies hair ageing as a biological field: pigment, signalling, stress, structure, metabolism, and the visible record those systems leave behind.
The field.
Hair is a record of biological change.
Hair is visible biology. Pigment, density, texture, shedding, stress load, and follicle function are signals from connected systems.
Visible biology. Human signal. Connected systems.
Hair is where stem-cell signalling, metabolism, oxidative pressure, nutrition, hormones, identity, and ageing become visible.The discoveries.
Three discovery lines made the field legible.
Across Harvard, Columbia, Nagoya, and the wider follicle-biology literature, researchers began to identify the pathways that make hair ageing tractable: stress signalling, human reversibility thresholds, Wnt and Endothelin coordination, oxidative pressure, stem-cell behaviour, and substrate support.
Discovery 02.
Human greying has a threshold.
Columbia quantified natural dark-to-white and white-to-dark transitions along individual hairs. The finding made hair ageing legible as a threshold phenomenon, not a fixed one-way line.
Rosenberg et al, 2021 · Columbia.
Discovery 03.
Luteolin preserved the signal.
In the strongest relevant model on file, Luteolin preserved endothelin signalling between keratinocyte and melanocyte stem cells and reduced senescent-cell burden in the bulge.
Iida et al, 2024 · Nagoya.
The synthesis.
Literature, materia medica, and computation had to be read together.
Hair Labs consolidates the literature, publishes the biology in the Journal, maps the mechanisms in Research, and formulates where the evidence, dose, and pairwise model hold.
01.
Journal.
The field is published first: open chapters, primary sources, and the biology before the product.
02.
Research.
The literature becomes method: drivers, mechanisms, rejections, references, and formulation logic.
03.
Formulation.
Only after the field is legible does the practice release a protocol from the work.
The computation.
AI-enabled literature mapping. Pairwise interaction modelling.
Generative models helped make thousands of pages of biology searchable by mechanism rather than by keyword. Hair Labs used that capability to map drivers, extract candidate compounds, compare constraints, and keep the literature auditable under advisory and formulation review.
01.
Map the corpus.
AI-enabled literature mapping structured the field by mechanism, driver, compound, and constraint so the evidence could be compared on common terms.
02.
Model the pairs.
Candidate compounds are read against one another: redox compatibility, cofactor dependency, methylation fit, absorption, dose, form, and the two-capsule envelope.
03.
Review what survives.
Published papers, formulation judgement, pharmacist manufacturing, and advisory review decide what enters the protocol.
Materia medica.
Compounds, sources, mechanisms.
Each candidate is read as materia medica: molecule, source, assay, dose, form, mechanism, and interaction. Named compounds from named plants are then tested against the literature and the pairwise model.
Kensington, London.
Arthur Corvin Powells.
Hair Labs was co-founded by Arthur Corvin Powells to bring published hair-ageing biology, materia medica, and computational formulation into one practice. The Journal is the public record of that work; Anti Grey 1.0 is the first formulation to leave it.
Arthur Corvin Powells · Co-founder · Kensington
Clinical counsel sits inside the practice.
The Clinical Advisory Board contributes clinical trichology, nutrition science, pigment biology, and pharmacy manufacturing review to the Hair Labs advisory system.
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§ 01
Penny James, IAT, IOT.
Consultant Trichologist · 30+ years clinical experience.
Hair Labs has achieved a formula that addresses key contributors to hair greying — including stress, nutrient gaps, and oxidative damage — offering an evidence-based way to help maintain natural hair colour.
London, United Kingdom. Practices in New York.
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§ 02
Dr Michael Ryan, MIT, AIT, PsyD.
Board-certified Trichologist · Women's hair health.
Maintaining natural hair pigmentation depends on preserving the biochemical balance required for melanogenesis within the follicle. Supporting this balance over time aligns with how pigment biology functions.
London, United Kingdom.
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§ 03
Dr Jerusa Brignardello.
Nutrition scientist · PhD, Imperial College London.
Adaptogens are plants studied for their potential to support the body's response to physical and psychological stress. Supporting a healthy stress response could be one important piece in maintaining hair pigmentation over time.
Oxford, United Kingdom.
